DOI: http://dx.doi.org/10.18203/2394-6040.ijcmph20213548

Knowledge and perceptions towards candidate COVID-19 vaccines among practicing physicians of Tamil Nadu: a cross-sectional pilot study

K. R. S. Sivapriya, A. Keerthana, Balaji Arumugam, R. Nivetha

Abstract


Background: The world is in the midst of a COVID-19 pandemic and WHO is working in collaboration with scientists, business and global health organizations to speed up the pandemic response and they are racing to find a vaccine. COVAX the largest and most diverse COVID-19 vaccine portfolio in the world launched by WHO. There are currently over 189 COVID-19 vaccine candidates under development, with 40 of these in the human trial phase. This study was done to assess the knowledge and perceptions towards candidate COVID-19 vaccines among practicing physicians.

Methods: A cross-sectional study were done among 129 practicing physicians using a semi-structured, validated, questionnaire through online Google forms after obtaining the informed consent. The data was analyzed using SPSS version 20.

Results: The study was done among 129 practicing physicians of which 65 (50.4%) were males and 64 (49.6%) were females and majority of them in the age group of 21-40 years (77.5%) with a mean age of 34.89±9.906 years. 82.2% of the participants were working with the clinical specialty of which 95 (73.6%) with 10 years of professional experience and 23 (17.8%) had 10-20 years of professional experience. Majority of the practicing physicians 92 (72.3%) have average knowledge towards COVID-19 vaccines. Overall, the physicians showed positive attitude towards COVID-19 vaccines and 107 (82.9%) said that COVID-19 vaccine was really needed to control the pandemic.

Conclusions: The study recommends promoting all precautionary and preventive measures of COVID-19 with a comprehensive training program for the practicing physicians before the implementation of COVID-19 vaccines which will support public engagement strategies and help to build preparedness for potential vaccine introduction. 


Keywords


COVID-19 vaccines, Perceptions, Physicians

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References


Zhou P, Yang XL, Wang XG, Hu B, Zhang L, Zhang W, et al. A pneumonia outbreak associated with a new coronavirus of probable bat origin. Nature. 2020;579(7798):270-3.

Yong CY, Ong HK, Yeap SK, Ho KL, Tan WS. Recent Advances in the Vaccine Development Against Middle East Respiratory Syndrome-Coronavirus. Front Microbiol. 2019;10:1781.

Le T, Andreadakis Z, Kumar A, Román RG, Tollefsen S, Saville M, et al. The COVID-19 vaccine development landscape. Nat Rev Drug Discov. 2020;19(5):305-6.

WHO. Fact sheet: Coronavirus disease 2019 (COVID-19) Situation Report-38. Available at: https://www.who.int/docs/default-source/corona viruse/situation-reports/20200227. Accessed on 1 July 2021.

WHO. Fact sheet: Draft landscape of COVID-19 candidate vaccines. Available at: https://www.who.int/publications/m/item/draft-landscape-of-covid-19-candidate-vaccines. Accessed on 1 July 2021.

Koirala A, JinJoo Y, Khatami A, Chiu C, Britton PN. Vaccines for COVID-19: the current state of play. Paediatr Respir Rev. 2020;35:43-9.

Zhu FC, Li YH, Guan XH, Hou LH, Wang WJ, Li JX, et al. Safety, tolerability, and immunogenicity of a recombinant adenovirus type-5 vectored COVID-19 vaccine: a dose-escalation, open-label, non-randomized, first-in-human trial. Lancet. 2020;395(10240):1845-54.

Zhu FC, Guan XH, Li YH, Huang J, Jiang T, Hou LH. Immunogenicity and safety of a recombinant adenovirus type-5-vectored COVID-19 vaccine in healthy adults aged 18 years or older: a randomized, double-blind, placebo-controlled, phase 2 trial. Lancet. 2020;396(10249):479-88.

Lai CC, Shih TP, Ko WC, Tang HJ, Hsueh PR. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease-2019 (COVID-19): the epidemic and the challenges. Int J Antimicrob Agents. 2020;55(3):105924.

WHO. Fact sheet: Coronavirus disease (COVID-19) vaccines. Available at: https://www.who.int/news-room/q-a-detail/coronavirus-disease-(covid-19)-vaccines. Accessed on 1 July 2021.

Dzieciolowska S, Hamel D, Gadio S, Dionne M, Gagnon D, Robitaille L, et al. COVID-19 vaccine acceptance, hesitancy and refusal among Canadian healthcare workers: a multi center survey. Am J Infect Control. 2021:0196-6553.

Verger P, Scronias D, Dauby N, Adedzi KA, Gobert C, Bergeat M, et al. Attitudes of healthcare workers towards COVID-19 vaccination: a survey in France and French-speaking parts of Belgium and Canada, 2020. Euro Surveill. 2021;26(3):2002047.

Bish A, Yardley L, Nicoll A, Michie S. Factors associated with uptake of vaccination against pandemic influenza: a systematic review. Vaccine. 2011;29(38):6472-84.

Lazarus JV, Ratzan SC, Palayew A, Gostin LO, Larson HJ, Rabin K, et al. A global survey of potential acceptance of a COVID-19 vaccine. Nat Med. 2020:1-4.

Peretti-Watel P, Seror V, Cortaredona S, Launay O, Raude J, Verger P, et al. COCONEL group a future vaccination campaign against COVID-19 at risk of vaccine hesitancy and politicisation. Lancet Infect Dis. 2020;20(7):769-70.

Papagiannis D, Malli F, Raptis DG, Papathanasiou IV, Fradelos EC, Daniil Z, et al. Assessment of knowledge, attitudes, and practices towards new coronavirus (SARS-CoV-2) of health care professionals in greece before the outbreak period. Int J Environ Res Public Health. 2020;17(14):4925.

Gagneux-Brunon A, Detoc M, Bruel S, Tardy B, Rozaire O, Frappe P, et al. Intention to get vaccinations against COVID-19 in French healthcare workers during the first pandemic wave: a cross sectional survey. J Hosp Infect. 2021;108:168-73.

Wang K, Wong ELY, Ho KF, Cheung AWL, Chan EYY, Yeoh EK, et al. Intention of nurses to accept coronavirus disease 2019 vaccination and change of intention to accept seasonal influenza vaccination during the coronavirus disease 2019 pandemic: a cross-sectional survey. Vaccine. 2020;38(45):7049-56.

Pădureanu V, Bogdan M, Subtirelu M, Padureanu R, Turcu-Stiolica A, Petresu F, et al. Perceptions of COVID-19 vaccination among healthcare professionals in Romania. Revista medico-chirurgicala a Societatii de Medici siNaturalisti din Iasi. 2020;124:454-60.

Muhammad S, Muhammad M, Rehman SU, Aqsa G, Saha N, Zaheer A, et al. Knowledge, attitude and practice among healthcare professionals regarding COVID-19: a cross-sectional survey from Pakistan. MedRxiv. 2021.

Konopińska J, Obuchowska I, Lisowski Ł, Dub N, Kozera M, Rękas M. Intention to get COVID-19 vaccinations among ophthalmology residents in Poland: a cross-sectional survey. Vaccines (Basel). 2021;9(4):371.

WHO. Accelerating a safe and effective COVID-19 vaccine. 2020.Accessed on 25Aug 2021. Available form: https://bit.ly/3koVPgj. Accessed on 20 July 2021.