DOI: http://dx.doi.org/10.18203/2394-6040.ijcmph20171304

Distribution of leptospirosis patients in Sri Lanka: a retrospective study

Nimantha Karunathilaka, Kithsiri Jayasekara, Ishara Chathurangani, Ranga Thudugala, Athige Rajith Silva, Wanigasekara Daya Ratnasooriya

Abstract


Background: Leptospirosis [LP] is zoonotic diseases and one of the main communicable diseases in Sri Lanka [SL]. SL is a tropical country in the Indian Ocean with favorable environmental and geographical conditions for dispersion of the LP infection. The aim of the study was to determine the pattern of distribution with possible environmental conditions/factors contributing to the LP in SL.

Methods: The study was carried out as retrospective study from 2009-14 throughout the all 25 administrative districts in SL.

Results: The multiple regression was performed to investigate any associations between the prevalence of LP and independent variable parameters namely, annual rainfall, average humidity, area of paddy lands and annual flood data. The results revealed that factors affecting prevalence of the LP in Sri Lanka can’t be investigated in toto. Seasonal analysis is needed in the wet and dry zones corresponding to the main Yala and Maha agricultural seasons. Annual rainfall is mainly associated with the prevalence of LP in the wet zone while agricultural environment associated with the prevalence of LP in the dry zone (p<0.05). Furthermore, geographical distribution, high annual water discharge and low precipitation of the river water provides favorable environment for dispersion of LP in the wet zone whilst large reservoirs with highly functioning cascades correlated in the dry zone in SL.

Conclusions: It is concluded that pattern of distribution with possible environmental conditions/factors contributing to the LP in SL is vary in the wet and dry zones. 


Keywords


Leptospirosis, Sri Lanka & Geographical distribution

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References


Department of Census and Statistics: Sri Lanka (SL). Statistical Abstract, 2016. Available at http://www.statistics.gov.lk/Abstract2014/Pages/chap1.htm. Accessed on 3 January 2017.

Manchanayake P, Bandara CMM. Water resources of Sri Lanka, National Science Foundation, Sri lanka, 1999.

Matthias M.A. Human leptospirosis caused by a new, antigenically unique Leptospira associated with a Rattus species reservoir in the Peruvian Amazon. PLoS Neglected Trop Dis. 2008;2:213.

Kumar P, Clark M. Essentials of Clinical Medicine 5th edition. Saunders, China: 2011.

Brooks GF, Butel JF, Morse SA. Leptospira and Leptospirosis. Med Microbio Singapore. 2004;8:338-40.

Sehgal C, Sugunan P, Vijayachari P. Leptospirosis disease burden estimation and surveillance networking in India. Southeast Asian J Trop Med Public Health. 2003;34(2):170-7.

Robertson C, Nelson TA, Stephen C. Spatial epidemiology of suspected clinical leptospirosis in Sri Lanka. Epidemiol Infect. 2011;140(4):731-43.

Faine SB, Adler B, Bolin C, Perolat P. Leptospira and Leptospirosis. Melbourne. Medi Sci. 1999.

Katz AR, Manea SJ, Sasaki DM. Leptospirosis on Kauai: investigation of a common source waterborne outbreak. American J Public Health. 1991;81(10):1310–2.

Annual Epidemiology Report, Sri Lanka (SL). Selected notifiable diseases reported by Medical Officers of Health, 2010. Available from http://ecdc.europa.eu/en/publications/Publications/1011_SUR_Annual_Epidemiological_Report_on_Communicable_Diseases_in_Europe.pdf. Accessed on 3 January 2017.

Annual Epidemiology Report, Sri Lanka (SL). Selected notifiable diseases reported by Medical Officers of Health, 2009. Available from http://ecdc.europa.eu/en/publications/Publications/1111_SUR_Annual_Epidemiological_Report_on_Communicable_Diseases_in_Europe.pdf. Accessed on 3 January 2017.

Annual Epidemiology Report, Sri Lanka (SL). Selected notifiable diseases reported by Medical Officers of Health. 2011. Available from http://ecdc.europa.eu/en/publications/Publications/annual-epidemiological-report-2013.pdf. Accessed on 1 January 2017.

Pappas G, Papadimitriou P, Siozopoulou V, Christou L, Akritidis N. The globalization of leptospirosis: worldwide incidence trends. Int J Infect Dis. 2008;12(4):351-7.

Agampodi S, Peacock SJ, Thevanesam V. The potential emergence of leptospirosis in Sri Lanka. Lancet Infect Dis. 2009;9(9):524-6.

Department of Census and Statistics, Sri Lanka (SL). Paddy Statistics, 2016 [cited 18 July 2016]. Available from http://www.statistics.gov.lk/

agriculture/Paddy%20Statistics/PaddyStats.htm. Accessed on 7 January 2017.

Department of Census and Statistics, Sri Lanka (SL). Mid-year Population Estimates by District & Sex, 2012–2016. Available from http://www.

statistics.gov.lk/PopHouSat/VitalStatistics/MidYearPopulation/Mid-year%20population%20by%

district.pdf. Accessed on 9 January 2017.

Department of Metrology, Sri Lanka (SL). Climate in Sri Lanka, 2016. Available from http://www.

meteo.gov.lk/index.php?option=com_content&view=article&id=13&Itemid=132〈=en. Accessed on 3 January 2017.

Epidemiology Unit, Sri Lanka (SL). Weekly Epidemiological Report, 2016. Available from http://www.epid.gov.lk/web/index.php?option=com_content&view=article&id=148&Itemid=449〈=en. Accessed on 28 January 2017.

Tangkanakul W, Smits HL, Jatanasen S, Ashford DA. Leptospirosis: an emerging health problem in Thailand. Southeast Asian J Trop Med Public Health. 2005;36(2):281-8.

Svircev Z, Marković SB, Vukadinov J, Stefan-Mikić S, Ruzić M, Doder R, et al. Leptospirosis distribution related to freshwater habitats in the Vojvodina region (Republic of Serbia). Sci China Life Sci. 2009;52(10):965-71.

Bonnag D, Jaroonyesama N, Harinsuta C. A clinical study of leptospirosis. J Med Assoc Thailand. 1965;48:231–45.

Jansen A, Schöneberg I, Frank, C, Alpers K, Schneider T, Stark K, et al. Leptospirosis in Germany. Emerging Infect Dis. 2005;11(7):1048-54.

Irrigation Department, Sri Lanka (SL). Annual Cropping Intensity for Major schemes, 2016. Available from http://www.irrigation.gov.lk/

index.php?option=com_content&view=article&id=299&Itemid=206〈=en. Accessed on 3 January 2017.

Karunathilaka RDN, Jayasekara JMKB, Bandara P, Thennakoon TMML, Silva ARN, Geethalankara AMAR. Epidemiological characteristics of the leptospirosis patients in Anuradhapura District, Sri Lanka. In proceedings of the 9th International Research Conference; 2016 Sep 7-8, KDU, Sri Lanka, Ratmalana, 2016: 249.