DOI: http://dx.doi.org/10.18203/2394-6040.ijcmph20211897

Assessment of quality of life among HIV infected people on antiretroviral therapy in a tertiary hospital, Karnataka

Anjan Sreeranga, P. Pavithra, Anand D. Meundi

Abstract


Background: With the availability of highly effective antiretroviral treatment, HIV is transforming into a chronic condition, whose management is now experiencing problems of other chronic diseases, where quality of life (QOL) has become an important component of overall assessment of health care and management. This study was conducted with the objective of assessing the QOL and factors influencing it in HIV infected people on antiretroviral therapy (ART).

Methods: A cross-sectional study was conducted at district ART center, Hassan. Purposive sampling was used to identify 148 HIV infected people on antiretroviral therapy, who were interviewed using a pretested questionnaire, assessing QOL with the World Health Organization (WHOQOL) HIV‑BREF.

Results: The average age of the study population was 37.69 years. Majority of them were males 54.7% compared to 45.3% of females. Most of them resided in rural areas (87.8%). The educational status of the subjects was poor with 33.8% of them being illiterates. The mean score was highest for spirituality and social relationships domain and least for psychological domain. Age, education and socioeconomic status did not have any influence on the QOL. There was significant difference between QOL scores and clinical stages. Individuals in stage I and II had better scores compared to stage 3 and 4. QOL scores decreased with decreasing CD4 count.

Conclusions: Our findings suggest that patient-reported measures of health status and related concepts may help provide a feasible, reliable and valid method to assess the impact of HIV/AIDS improve patient outcomes.

 


Keywords


HIV, AIDS, ART, Quality of life

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References


National AIDS Control. Organization. National Strategic Plan for HIV/AIDS and STI 2017 – 2024, National AIDS Control Organisation, Ministry of Health and Family Welfare, Government of India, New Delhi; 2017. Available at: http://naco.gov.in/ sites/default/files/Paving%20the%20Way%20for%20an%20AIDS%2015122017.pdf. Accessed on 3 March 2021.

WHO. The World Health Organisation Quality of Life (WHOQOL)-HIV BREF, 2002. Available at: http://www.who.int/substanceabuse/research_tools/en /english_whoqol.pdf.. Accessed on 30 March 2021.

Nirmal B, Divya KR, Dorairaj VS, Venkateswaran K. Quality of life in HIV/AIDS patient’s: a cross sectional study in south India. Ind J Sexual Transmit Dis AIDS. 2008;29(1):15-7.

Wig N, Lekshmi R, Pal H, Ahuja V, Mittal CM, Agarwal SK. The impact of HIV/AIDS on the quality of life: a cross sectional study in north India. Indian J Med Sci. 2006;60(1):3-12.

Marashi T, Garg S, Gupta VK, Singh MM, Sinha Pragya, Dewan R, et al. Assessment of quality of life among HIV positive people attending tertiary hospital of Delhi, India. J Commun Dis. 2009;41(2):101-8.

Shriharsha C, Rentala S. Quality of life among people living with HIV/AIDS and its predictors: a cross-sectional study at ART center, Bagalkot, Karnataka. J Family Med Prim Care. 2019;8(3):1011-6.

Alvi Y, Khalique N, Ahmad A, Shah MS, Faizi N. Quality of life among people living with HIV/AIDS receiving highly active anti‑retroviral therapy: a domain‑based analysis. Indian J Community Fam Med. 2020;6(2):125-31.

Lamkan AS, Aggarwal A. Assessing quality of life of people living with HIV/ AIDS in Manipur: an in-depth analysis. J Commun Dis. 2019;51(2):8-15.

Santos ECM, Junior IF, Lopes F. Quality of life of people living with HIV/AIDS in São Paulo, Brazil. Rev Saúde Pública. 2007;41(2).

Miners AH, Sabin CA, Mocroft A, Youle M, Fisher M, Johnson M. Health-related quality of life in individuals infected with HIV in the era of HAART. HIV Clin Trials. 2001;2(6):484-92.

Nieuwkerk PT, Gisolf EH, Reijers MHE, Lange JMA, Danner SA, Sprangers MAG. Long-term quality of life outcomes in three antiretroviral treatment strategies for HIV-1 infection. AIDS. 2001;15(15):1985-91.

Tolla L. Measuring the quality of life (QOL) of people living with HIV/AIDS (PLWHA) with highly active antiretroviral therapy (HAART) in Addis Ababa Zenebework Hospital. Ethiopia. 2006.

Osei-Yeboah J, Owiredu WKBA, Norgbe GK, Lokpo SY. Quality of life of people living with HIV/AIDS in the Ho municipality, Ghana: a cross-sectional study. AIDS Res Treat. 2017.

Carballo E, Cadarso-Suárez C, Carrera I, Fraga J, Fuente JDL, Ocampo A, et al. Assesssing health related quality of life and adherence to antiretroviral therapy. Qual Life Res. 2004;13(3):587-9.

Casado A, Consiglio E, Podzamczer D, Badia X. Highly active antiretroviral treatment (HAART) and health-related quality of life in naive and pretreated hiv-infected patients. HIV Clin Trials. 2001;2(6):477-83.

Hsiung P, Fang C, Chang Y, Chen M, Wang J. Comparison of WHO-QOL Bref with SF-36 in patients with HIV infection. Qual Life Res. 2005;14(1):141-50.

Yen CF, Tsai JJ, Lu PL, Chen YH, Chen TC, Chen PP, et al. Quality of life and its correlates in HIV/AIDS male outpatients receiving highly active antiretroviral therapy in Taiwan. Psychiatry Clin Neurosci. 2004;58(5):501-6.

Liu C, Ostrow D, Detels R, Hu Z, Johnson L, Kingsley L, et al. Impacts of HIV infection and HAART use on quality of life. Qual Life Res. 2006;15(6):941-9.

Chandra PS, Gandhi C, Satishchandra P, Kamat A, Desai A, Ravi V, et al. Quality of life in HIV subtype C infection among asymptomatic subjects and its association with CD4 counts and viral loads-a study from South India. Qual Life Res. 2006;15:1597-605.

Bajunirwe F, Tisch DJ, King CH, Arts EJ, Debanne SM, Sethi AK. Quality of life and social support among patients receiving antiretroviral therapy in Western Uganda. AIDS Care. 2009;21(3):271-9.

Liu C, Weber K, Robison E, Hu Z, Jacobson LP, Gange SJ. Assessing the effect of HAART on change in quality of life among HIV-infected women. AIDS Res Ther. 2006;3:1186.

Wang H, Zhou J, He G, Luo Y, Li X, Yang A, et al. Consistent ART adherence is associated with improved quality of life, CD4 counts, and reduced hospital costs in central China. AIDS Res Hum Retroviruses. 2009;25(8):757-63.

Alibhai A, Martin LJ, Kipp W, Konde-Lule J, Saunders LD, Rubaale T, et al. Quality of life of HIV patients in a rural area of western Uganda: impact of a community-based antiretroviral treatment program. Curr HIV Res. 2010;8(5):370-8.