DOI: http://dx.doi.org/10.18203/2394-6040.ijcmph20205694

Impact of severity of diabetic retinopathy on quality of life in type 2 Indian diabetic patients

Preeti Yadav, S.V. Singh, Manisha Nada, Monika Dahiya

Abstract


Background: Diabetes mellitus is a global public health challenge of 21st century and diabetic retinopathy is a common complication of long standing and poorly controlled diabetes which hampers patient’s physical, social and emotional well-being leading to poor quality of life. Objective was to study the correlation between severity of diabetic retinopathy and quality of life in type II DM patients.

Methods: A prospective, longitudinal and observational study was conducted in 120 patients of type II diabetes with diabetic retinopathy in a tertiary eye care centre of North India over a period from Feb. 2019 to March 2020. After doing initial ocular and systemic examination, each patient was interviewed in their local language as per NEI-VFQ-25 questionnaire. The response was calibrated quantitatively and total QoL score was calculated.

Results: Out of 120 patients of diabetic retinopathy, QoL Score was 69.8-88.8 in mild NPDR, 53.2-72.4 in moderate, 37.8-58.4 in severe NPDR and 22.4-42.2 in PDR with statistically significant difference (p<0.001). Median QoL Score was highest in mild NPDR patients and lowest in PDR, which signifies that quality of life deteriorates with severity of DR.

Conclusions: Diabetic retinopathy has an adverse effect on the QoL, which increases with severity of DR.


Keywords


Diabetic retinopathy, Diabetes mellitus, Quality of life

Full Text:

PDF

References


Wild S, Rogic G, Green A, Sicree R, King H. Global prevalence of diabetes, estimates for the year 2000 and projections for 2030. Diabetes Care. 2004;27:1047-53.

Ferris III FL, Patz A. Macular edema: a complication of diabetic retinopathy. Surv Ophthalmol. 1984;28(1):452-61.

Klein R, Klein BK, Moss SE. The Wisconsin epidemiologic study of diabetic retinopathy IV: diabetic macular edema. Ophthalmology. 1984;91(12):1464-74.

Howes SC, Caelli T, Mitchell P. Contrast sensitivity in diabetics with retinopathy on health-related quality of life. Curr Opin Ophthalmol. 2005;16(4):155-9.

Sokol S, Moskowitz A, Skarf B, Evans R, Molitch M, Senior B. Contrast sensitivity with and without background retinopathy. Arch Ophthalmol. 1985;103(1):51-4.

Mangione CM, Lee PP, Gutierrez PR, Spritzer K, Berry S, Hays RD. Development of the 25-list-item National Eye Institute Visual Function Questionnaire. Arch Ophthalmol. 2001;119(7):213-20.

Gabrielian, Hariprasad SM, Jager RD, Green JL, Mieler WF. The utility of visual function questionnaire in the assessment of the impact of diabetic retinopathy on vision related quality of life. Eye. 2010;24(1):29-35.

Steinberg EP, Tielsch JM, Schein OD, Javitt JC, Sharkey P, Cassard SD. The VF-An index of functional impairment in patients with cataract. Arch Ophthalmol. 1994;112(5):630-8.

McClure TM, Choi D, Becker T, Cioffi GA, Mansberger SL. The effect of visual impairment on vision-related quality of life in American Indian/ Alaska Natives. Opthalmic Epidemiol. 2009;16(2):128-35.

Fenwick EK, Pesudovs K, Khadka J, Dirani M, Rees G, Wong TY, et al. The impact of diabetic retinopathy on quality of life: qualitative findings from an item bank development project. Qual Life Res. 2012;21(1):771-82.

Ozawa GY, Bearse MA Jr Adams AJ. Male-female differences in diabetic retinopathy. Curr Eye Res. 2015;40(2):234-46.

Niveditha H, Yogitha C, Liji P, Sundeep S, Himanshu NV, Vinutha BV, et al. Clinical correlation of HbA1c and diabetic nephropathy with diabetic retinopathy. J Evol Med and Dent Sci. 2013;2(9):430-6.

Pereira DM, Shah A, D’Souza M, Simon P, George T, D’Souza N. Quality of life in people with diabetic retinopathy: Indian study. J Clin Diagn Res. 2017;11:1-6.

Chaturvedi N, Stephenson JM, Fuller JH. The relationship between socioeconomic status and diabetes control and complications in the EURODIAB IDDM Complications Study. Diabetes care. 1996;19(5):423-30.

Larsson D, Lager I, Nilsson PM. Socio-economic characteristics and quality of life in diabetes mellitus: Relation to metabolic control. Scand J Public Health. 1999;27(2):101-5.

Hanninen J, Takala J, Keinanen KS. Quality of life in NIDDM patients assessed with the SF‐20 questionnaire. Diabetes Res Clin Pract. 1998;42(1):17-27.

Alcubierre N, Rubinat E, Traveset A, Martinez A, Hernandez M, Jurjo C, et al. A prospective cross sectional study on quality of life and treatment satisfaction in type 2 diabetic patients with retinopathy without other major late diabetic complications. Health Qual Life Outcomes. 2014;12:131-4.