Role of sleep and stress in metabolic syndrome: a community based cross sectional study in Rishikesh, Uttarakhand

Authors

  • Senkadhirdasan Dakshinamurthy Department of Community and Family Medicine, AIIMS, Rishikesh, Uttarakhand, India
  • Vartika Saxena Department of Community and Family Medicine, AIIMS, Rishikesh, Uttarakhand, India
  • Ranjeeta Kumari Department of Community and Family Medicine, AIIMS, Rishikesh, Uttarakhand, India
  • Anissa Atif Mirza Department of Biochemistry, AIIMS, Rishikesh, Uttarakhand, India
  • Minakshi Dhar Department of Medicine, AIIMS, Rishikesh, Uttarakhand, India
  • Ashutosh Mishra Department of Community and Family Medicine, AIIMS, Rishikesh, Uttarakhand, India

DOI:

https://doi.org/10.18203/2394-6040.ijcmph20203922

Keywords:

Cardiometabolic risk, Epworth sleepiness scale, MetS, NCEP ATP 3 criteria, Non-communicable diseases, Perceived stress scale, Uttarakhand

Abstract

Background: Sleep disturbances and stress may intervene with the physiological processes in human body and act as a modulator of metabolic homeostasis. The aim and objectives of the study were to estimate the person’s average sleep propensity; to estimate the stress level in the study subjects; and to determine the association of sleep and stress with metabolic syndrome.

Methods: A community based cross sectional study was conducted in an urban area of Rishikesh. Sample size was calculated to be 478. Data was entered and analyzed using SPSS Version 20.0. Chi-square test was used to examine the association between categorical variables. A p value of <0.05 was considered significant.

Results: It was observed that different levels of stress did not have any significant association with metabolic syndrome (MetS) though the odds among individuals with moderate stress were 1.1 times (95% CI 0.6-2.2) higher than those with low stress. The overall sleepiness grading was not significantly associated with Metabolic Syndrome. However, people with mild excessive daytime sleepiness have 4.7 times (95% CI 1.2-18) higher odds of MetS as compared to those with low normal daytime sleepiness. Those with moderate excessive day sleepiness had 1.59 times (95% CI 0.3-8) higher odds of MetS, however it was not statistically significant.

Conclusions: Mild excessive daytime sleepiness was associated with an increased risk of metabolic syndrome. People with perceived stress are having higher chance of getting MetS.

References

Reaven GM. Banting lecture 1988: role of insulin resistance in human disease. Diabetes. 1988;37:1595-607.

Executive Summary of the Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). JAMA. 2001;285:2486–97.

Deepa M, Farooq S, Datta M, Deepa R, Mohan V. Prevalence of metabolic syndrome using WHO, ATPIII and IDF definitions in Asian Indians: the Chennai urban rural epidemiology study (CURES‐34). Diabetes Metab Res Rev. 2007;23(2):127-34.

Gupta R, Deedwania PC, Gupta A, Rastogi S, Panwar RB, Kothari K. Prevalence of metabolic syndrome in an Indian urban population. Int J Cardiol. 2004;97(2):257-61.

Can SH, Hendy HM. Behavioral variables associated with obesity in police officers. Ind Health. 2014;52(3):240-7.

Chandola T, Brunner E, Marmot M. Chronic stress at work and the metabolic syndrome: prospective study. BMJ. 2006;332(7540):521-5.

Bixler EO, Vgontzas AN, Lin HM, Calhoun SL, Vela-Bueno A, Kales A. Excessive daytime sleepiness in a general population sample: the role of sleep apnea, age, obesity, diabetes, and depression. J Clin Endocrinol Metab. 2005;90:4510-5.

Akbaraly TN, Jaussent I, Besset A, Bertrand M, Barberger-Gateau P, Ritchie K, et al. Sleep complaints and metabolic syndrome in an elderly population: the Three-City Study. Am J Geriatr Psychiatr. 2015;23:818-28.

Fu Y, Xu H, Xia Y, Qian Y, Li X, Zou J, et al. Excessive daytime sleepiness and metabolic syndrome in men with obstructive sleep apnea: a large cross-sectional study. Oncotarget. 2017;8(45):79693.

Singh A, Shenoy S, Sandhu JS. Prevalence of metabolic syndrome and its risk factors among urban Sikh population of Amritsar. J Postgraduate Med Educ Res 2015;49:18.

Rishikesh Nagar Palika Parishad City Population Census 2011-2019. Uttarakhand. Census2011.co.in. 2019. Available from: https://www.census2011. co.in/data/town/800313-rishikesh-uttarakhand.html. Accessed on 26 October 2019.

STEPwise approach to surveillance (STEPS). World Health Organization. 2019. Available from: https://www.who.int/ncds/surveillance/steps/en/.

Cohen S, Kamarck T, Mermelstein R. A global measure of perceived stress. J Health Soc Behav. 1983:385-96.

Johns MW. The clinical assessment of daytime sleepiness in patients with obstructive sleep apnea. In: Fabiani M, ed. Surgery for snoring and obstructive sleep apnea syndrome. Kugler publications, The Hague: Netherlands; 2003:283-295.

Janczura M, Bochenek G, Nowobilski R, Dropinski J, Kotula-Horowitz K, Laskowicz B, et al. The relationship of metabolic syndrome with stress, coronary heart disease and pulmonary function-An occupational cohort-based study. PLoS One. 2015;10(8):e0133750.

Yoshioka M, Ayabe M, Yahiro T. Long-period accelerometer monitoring shows the role of physical activity in overweight and obesity. Int J Obes. 2005;29:502-8.

Wang Q, Zhang X, Fang L, Guan Q, Gao L, Li Q. Physical activity patterns and risk of type 2 diabetes and metabolic syndrome in middle-aged and elderly northern Chinese adults. J Diabetes Res. 2018;2018.

Kim CE, Shin S, Lee HW, Lim J, Lee JK, Shin A, et al. Association between sleep duration and metabolic syndrome: a cross-sectional study. BMC Public Health. 2018;18(1):720.

Chandola T, Britton A, Brunner E, Hemingway H, Malik M, Kumari M, et al. Work stress and coronary heart disease: what are the mechanisms? Eur Heart J. 2008;29:640-8.

Borráz-León JI, Cerda-Molina AL, Mayagoitia-Novales L. Stress and cortisol responses in men: differences according to facial symmetry. Stress. 2017;20(6):573-9.

Dickerson SS, Kemeny ME. Acute stressors and cortisol responses: a theoretical integration and synthesis of laboratory research. Psycholog Bull. 2004;130(3):355.

Kurina LM, Schneider B, Waite LJ. Stress, symptoms of depression and anxiety, and cortisol patterns in working parents. Stress Health. 2004;20(2):53-63.

Bediwy AS, Mansour YM, Ali EA. Excessive daytime sleepiness among patients with metabolic syndrome. Egyptian J Chest Dis Tubercul. 2016;65(1):259-63.

Bixler EO, Vgontzas AN, Lin HM, Calhoun SL, Vela-Bueno A, Kales A. Excessive daytime sleepiness in a general population sample: the role of sleep apnea, age, obesity, diabetes, and depression. J Clin Endocrinol Metab. 2005;90:4510-5.

Akbaraly TN, Jaussent I, Besset A, Bertrand M, Barberger-Gateau P, Ritchie K, et al. Sleep complaints and metabolic syndrome in an elderly population: the three-city study. Am J Geriatr Psychiatr. 2015;23:818-28.

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Published

2020-08-28

How to Cite

Dakshinamurthy, S., Saxena, V., Kumari, R., Mirza, A. A., Dhar, M., & Mishra, A. (2020). Role of sleep and stress in metabolic syndrome: a community based cross sectional study in Rishikesh, Uttarakhand. International Journal Of Community Medicine And Public Health, 7(9), 3553–3558. https://doi.org/10.18203/2394-6040.ijcmph20203922

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Original Research Articles