A cross-sectional study among defaulters of DOTS under RNTCP in tuberculosis units of Solapur city

Authors

  • Anand D. Gosavi District Training Team, Palghar, Maharashtra, India
  • Viresh A. Nandimath Department of Community Medicine, Dr. Vaishampayan Memorial Government Medical College, Solapur, Maharashtra, India
  • Suresh K. Mangulikar Department of Community Medicine, Dr. Vaishampayan Memorial Government Medical College, Solapur, Maharashtra, India

DOI:

https://doi.org/10.18203/2394-6040.ijcmph20190605

Keywords:

Defaulter, DOTS, Employment, Poverty, Socio-economic status

Abstract

Background: Tuberculosis (TB) is a specific infectious disease caused by mycobacterium tuberculosis affecting pulmonary and extra-pulmonary organs. Default is one of the unfavorable outcomes for patients on DOTS and represents an important challenge for the control programme. Inadequate treatment adherence is considered as a potential cause of drug resistance. This study was conducted ascertain causes of defaults & to study socio-demographic corelates of defaulters.

Methods: A cross-sectional study was conducted from 1st January 2014 to 31st December 2014. All default patients registered from 1st January 2014 to 31st December 2014 under RNTCP in both Tuberculosis Units of Municipal Corporation are considered for this study.

Results: Total 104 cases of defaulters were registered under RNTCP in both TB units; 83 (79.8%) defaulters were males and remaining 21 (21.2%) were females and difference was statistically significant. Side effects of DOTS drugs were the most common reason of defaulting the treatment. Default of DOTS was significantly associated with socioeconomic status, educational status, addiction, religion and marital status of the patients.

Conclusions: Poverty has effect on illness and completion of treatment.

References

Al-Sharrah YA. The Arab Tradition of Medical Education and its Relationship with the European Tradition. Springer. 2003;33(4):413-25.

Kishore J. National Health Programs of India. 10th ed. Century publications; 2013.

Balasubramanian R, Garg R, Santha T, Gopi PG, Subramani R, Chandrasekaran V, et al. Gender disparities in tuberculosis: Report from a rural DOTS programme in South India. Int J Tuberc Lung Dis. 2004;8:323-32.

Arora VK, Singla N, Sarin R. Profile of geriatric patients under DOTS in Revised National Tuberculosis Control Programme. Indian J Chest Dis Allied Sci. 2003;45:2315.

Santha T, Garg R, Frieden TR, Chandrasekaran V, Subramani R, Gopi PG, et al. Risk factors associated with default, failure and death amontuberculosis patients treated in a DOTS programme in Tiruvallur District, South India, 2000. Int J Tuberc Lung Dis. 2002;6:780-8.

Jaiswal A, Singh V, Ogden JA, Porter JD, Sharma PP, Sarin R, et al. Adherence to tuberculosis treatment: Lessons from the urban setting of Delhi, India. Trop Med Int Health. Delhi, India. Trop Med Int Health. 2003;8:625-33.

Kang CI, Choi CM, Kim DH, Kim CH, Lee DJ, Kim HB, et al. Pulmonary tuberculosis in young Korean soldiers: incidence, drug resistance and treatment outcomes. Int J Tuberc Lung Dis. 2006;10(9):970-4.

Achanta S, Jaju J, Kumar AMV, Nagaraja SB, Shamrao SRM, Bandi SK, et al. Tuberculosis Management Practices by Private Practitioners in Andhra Pradesh, India. PLOS ONE. 2013;8(8):1-10.

Selvam JM, Wares F, Perumal M, Gopi PG, Sudha G, Chandrasekaran V, et al. Health-seeking behaviour of new smear-positive TB patients under a DOTS programme in Tamil Nadu, 2003. Int J Tuberc Lung Dis. 2007;11(2):161-7.

Amoran OE, Osiyale OO, Lawal KM. Pattern of default among tuberculosis patients on directly observed therapy in rural primary health care centres in Ogun State, Nigeria. J Infect Dis Immunity. 2011;3(5):90-5.

Chandrasekaran V, Gopi PG, Subramani R, Thomas A, Jaggarajamma K, Narayanan PR. Default during the intensive phase of treatment under DOTS programme. Indian J Tuberc. 2002;52:197-202.

Chadha SL, Bhagi RP. Treatment outcome in Tuberculosis patients placed under directly observed treatment short course (DOTS)- A cohort Study. Ind J Tub. 2000;47:155-8.

Dodor EA, Afenyadu GY. Factors associated with tuberculosis treatment default and completion at the Effia-Nkwanta Regional Hospital in Ghana. Trans R Soc Trop Med Hyg. 2005;99(11):827-32.

Navaratnasingam J, Seneviratne RA. Factors contributing to medication non-compliance of newly diagnosed smear-positive pulmonary tuberculosis patients in the district of Colombo, Sri Lanka. Asia Pac J Public Health. 2008;20(3):214-23.

Karim F. Socio-economic Divides in Tuberculosis Control Study of Smear-Positive TB Prevalence, Care Seeking Behaviour and Role of Informal Healthcare Providers, Research and Evaluation Division, BRAC 2009, Research Monograph Series No. 41, 2009.

Sophia VVH, Balasangameswara PS, Jagannatha VN, Saroja, Kumar P. Defaults among tuberculosis patients treated under DOTS in Bangalore city: A search for solution. Ind J Tub. 2003;50:185.

Frank R. Spencer MD. A review of tuberculosis. Bri J Community Med. 2005;55(1):5.

Lamsal DK, Lewis OD, Smith S, Jha N. Factors related to defaulters and treatment failure of tuberculosis patients in the DOTS program in the Sunsari District of Eastern Nepal. SAARC J Tuberculosis, Lung Dis HIV/AIDS. 2009;6(1):47-55.

Jain RF. Faulty prescription, an avoidable cause of MDR and compliance with treatment. Indian J TB. 1998;45:141-4.

Vijay S, Kumar P, Chauhan LS, Vollepore BH, Kizhakkethil UP, Rao SG. Risk factors associated with default among new smear positive TB patients treated under DOTS in India. 2010;4(5):e10043.

Pandit N, Choudhary SK. A study of treatment compliance in directly observed therapy for tuberculosis. Indian J Community Med. 2006;31(4):10-2.

Hasker E, Khodjikhanov M, Usarova S, Umi, Asamidinov, Yuldashova U, et al. Default from tuberculosis treatment in Tashkent, Uzbekistan; Who are these defaulters and why do they default? BMC Infect Dis. 2008;8:97.

Santha T, Garg R, Frieden TR, Chandrasekaran V, Subramani R, Gopi PG, et al. Risk factors associated with default, failure and death among tuberculosis patients treated in a DOTS programme in Tiruvallur District, South India, 2000. Int J Tuberc Lung Dis. 2002;6:780-8.

Chadha SL, Bhagi RP. Treatment outcome in Tuberculosis patients placed under directly observed treatment short course (DOTS)- A cohort Study. Ind J Tub. 2000;(47):155-8.

Pedro Suarez G. Second-line treatment for chronic tuberculosis. Lancet. 2002;360(9343):1430-2.

Jaggarajamma K, Sudha G, Chandrasekaran V, Nirupa C, Thomas A, Santha T, et al. Reasons for non-compliance among patients treated under Revised National Tuberculosis Control Programme, Tiruvallur district, South India. Indian J Tuberc. 2007;54:130-5.

Downloads

Published

2019-02-22

How to Cite

D. Gosavi, A., A. Nandimath, V., & K. Mangulikar, S. (2019). A cross-sectional study among defaulters of DOTS under RNTCP in tuberculosis units of Solapur city. International Journal Of Community Medicine And Public Health, 6(3), 1167–1171. https://doi.org/10.18203/2394-6040.ijcmph20190605

Issue

Section

Original Research Articles