DOI: http://dx.doi.org/10.18203/2394-6040.ijcmph20185079

Seasonal variation of allergy profile of patients visiting a tertiary care hospital in hilly areas of Himachal Pradesh

Manpreet S. Nanda, Rama Devi

Abstract


Background: Allergic diseases are very common and are caused by allergen whose role varies according to climate changes. Not many studies are available regarding the same in our region. Skin prick test is a diagnostic procedure for allergy testing. The aim of the present study was to find out the seasonal variation of different allergies in our region.

Methods: A total of 686 patients with allergic complaints were assessed for age and sex distribution, seasonal variation of number of allergy patients and seasonal variation of patient symptoms. 608 patients who gave consent and were found fit for skin prick tests underwent the tests and were analysed for allergy profile of the patients in different seasons.

Results: The majority of patients were females and of younger age group. The majority of the patients had nasal symptoms and these symptoms were more in summer and rainy season during which pine mix and grass pollen were common allergens. Pulmonary symptoms were maximum in winters with dust mite and moulds being the common allergens. Dust mite was overall the most common allergen involved. Sensitization to allergens was less in winter months.

Conclusions: This study focussed on seasonal variation of allergies and found pine mix and grass pollens to be major cause of nasal allergy and dust mite and mould mix to mainly cause pulmonary symptoms.


Keywords


Allergens, Seasonal variation, Sensitization, Skin prick tests

Full Text:

PDF

References


Brozek JL, Bousquet J, Baena‑Cagnani CE, Bonini S, Canonica GW, Casale TB, et al. Allergic rhinitis and its impact on asthma (ARIA) guidelines:2010 revision. J Allergy Clin Immunol. 2010;126:466‑76.

Gell PG, Coombs RR, editors. Clinical Aspects of Immunology. Oxford, England: Blackwell; 1963.

Bousquet J, Khaltaev N, Cruz AA, Denburg J, Fokkens WJ, Togias A, et al. Allergic rhinitis and its impact on asthma (ARIA) 2008 update (in collaboration with the world health organization, GA(2) LEN and AllerGen). Allergy. 2008;63(86):8-160.

D’Amato G, Liccardi G, D’Amato M, Cazzola M. Outdoor air pollution, climatic changes and allergic bronchial asthma. Eur Respir J. 2002;20 (3):763-76.

Nelson H. Diagnostic procedures in allergy:allergy skin testing. Annals of allergy. 1983;51(4):411-8.

Ten RM, Klein JS, Frigas E. Allergy skin testing. Mayo Clin Proc. 1995;70:783-4.

Nanda MS, Singh K, Devi R. Allergy profile of patients visiting a tertiary care hospital in hilly areas of Solan, Himachal Pradesh, India. J Clin Diagnos Res. 2018;12(2):1-3.

Desalu OO, Salami AK, Iseh KR, Oluboyo PO. Prevalence of self reported allergic rhinitis and its relationship with asthma among adult Nigerians. J Investig Allergol Clin Immunol. 2009;19(6):474-80.

Rasool R, Shera IA, Nissar S, Shah ZA, Nayak N, Siddiqi MA, et al. Role of skin prick test in allergic disorders:a prospective study in Kashmiri population in light of review. Indian J Dermatol. 2013;58(1):12-7.

Wiqar SA. Allergic rhinitis in allergy and asthma-a clinical primer. IJCP. 1999:65.

Oh JW, Lee HB, Kang IJ, Kim SW, Park KS, Kook MH, et al. The revised edition of Korean calendar for allergenic pollens. Allergy Asthma Immunol Res. 2012;4:5-11.

Abbas AK, Lichtman AH, Pober JS. Cellular and molecular immunology. 2nd ed. Philadelphia, PA: WB Saunders; 1994.

Oladeji S, Nwawolo C, Adewole O. Allergic rhinitis among adult bronchial asthmatic patients in Lagos, Nigeria. J West Afr Coll Surg. 2013;3(2):01-14.

Giridhar BH, Kumar S, Verma AK, Singh A, Kumar D, Prasad R et al. A study on profile of allergens sensitivity and associated factors in naso-bronchial allergic patients. Natl J Med Res. 2012;2(1):70-6.

Han ER, Choi IS, Lee S, Cho YW. Airway hyperresponsiveness-related aeroallergens in suspected asthma. Korean J Asthma Allergy Clin Immunol. 2007;27:105-10.

Gergen PJ, Turkeltaub PC. The association of individual allergen reactivity with respiratory disease in a national sample:data from the second National Health and Nutrition Examination Survey, 1976-80 (NHANES II). J Allergy Clin Immunol. 1992;90:579-88.

Sharma R, Gaur SN, Singh VP, Singh AB. Association between indoor fungi in Delhi homes and sensitization in children with respiratory allergy. Med Mycol. 2012;50:281-90.

Choi IS, Ki WJ, Kim TO, Han ER, Seo IK. Seasonal factors influencing exercise-induced asthma. Allergy Asthma Immunol Res. 2012;4:192-8.

Kim E, Kim MJ, Lee JS, Yoon JS. Association between autumnal exacerbation and Dermatophagoides pteronyssinus specific IgE in childhood asthma. Pediatr Allergy Respir Dis. 2007;17:242-8.