A study on associations and influence of health determinants on systolic and diastolic blood pressure

Sreenivasa V. Yalamanchili


Background: The aim of the study was to assess the prevalence of hypertension among Indian urban educated population and evaluate the association of various modifiable and non-modifiable risk factors on the development of systolic blood pressure (SBP) and diastolic blood pressure (DBP).

Methods: The retrospective study comprised of medical data obtained from 175 individuals who had undergone routine annual medical check-up during the period 2016 -2017. The data was analysed and interpreted using summary statistics, correlations and linear regression analysis. Most of the variables were measured values.

Results: Out of 175 reports analysed, 40 (22.9%) individuals comprising of 29 males and 11 females were found to be hypertensives. Isolated systolic hypertension was present in 4 (2.3%) individuals, isolated diastolic hypertension in 26 (14.9%) individuals and in 10 (5.7%) individuals both systolic and diastolic blood pressure was raised. Significant correlations were observed. Multiple linear regression showed significant positive influence of DBP, age and BMI on SBP whereas serum vitamin D level and left ventricular cardiac ejection fraction was negatively influencing SBP (R²=0.638, p=0.000). furthermore, multiple regression analysis with DBP as the dependent variable showed SBP, and serum vitamin D level to be the significant influencing determinants (R²=0.602, p=0.000).

Conclusions: The present study on the Influence of modifiable and non-modifiable risk factors on development of SBP and DBP improves knowledge for better preventive strategies.


Hypertension, Systolic blood pressure, Diastolic blood pressure, Health determinants

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