Quality of life in diabetic subjects with respect to metabolic syndrome: a case control study

Mahesh V., Latha K., Muninarayana C., Ravishankar S.


Background: Diabetes is a chronic non-communicable disease, leading to many complications and disability. With co morbidities it leads to a substantial decrease in the patients’ quality of life (QoL). In diabetics, psychosocial factors such as depression are stronger predictors of medical outcomes such as hospitalization and death than are physical and metabolic factors such as presence of complications, body mass index, or HbA1c level. Hence this study was conducted with the objectives to correlate the quality of life (QoL) domains with metabolic syndrome parameters among diabetic patients.

Methods: Hospital based case control study was done for a period of 3 months among 180 diabetics and non-diabetics in a rural tertiary care centre. Information on socio- demographic profile, diabetic history was collected using a pretested and structured questionnaire. Quality of life was assessed by WHOQOL-BREF. Statistical analysis was carried out by using SPSS 22 Version. Chi-square and independent t-test was the statistical test.

Results: Majority of subjects in both groups were females, 56.7% and 54.4% in cases and controls respectively. Mean age of cases and control was 57.9±11.7 years and 57.4±11.2 years respectively. Significant association between diabetes and metabolic syndrome was observed. Quality of life was significantly low among diabetics with metabolic syndrome than without metabolic syndrome.

Conclusions: Quality of life with respect to physical, psychological and social domain among diabetics with metabolic syndrome was reduced significantly. 


Quality of life, Diabetes mellitus, Metabolic syndrome

Full Text:



Nagpal J, Kumar A, Kakar S, Bhartia A. The development of quality of life instrument for Indian diabetes patients (QOLID): a validation and reliability study in middle and higher income groups. J Asso Physicians India. 2010;58:295-304.

Fal AM, Jankowska B, Uchmanowicz I. Type 2 diabetes quality of life patients treated with insulin and oral hypoglycemic medication. Bio Med Central. 2011;48(3):237-42.

Richard R, Rubin CDE. Diabetes and quality of life. Diabetes Spectrum. 2000;13:21.

Orley J. Introduction, administration, scoring and generic version of the assessment field trial version. Programme on mental health. World Health Organization. 1996.

The World Health Organization Quality of Life (WHOQOL)-BREF. World Health Organization 2004.

World Health Organization. Definition, diagnosis and classification of diabetes mellitus and its complications: Report of a WHO Consultation. Available at: http:// Accessed on 11January 2016.

The IDF consensus worldwide definition of the metabolic syndrome 2006. Available from: . Accessed on 15 June 2016.

Misra A, Wasir JS, Pandey RM. An evaluation of candidate definitions of the metabolic syndrome in adult Asian Indians. Diabetes Care. 2005;28:398-03.

Srinivas HK, Venkatesha M, Prasad R. Quality of life assessment among type 2 diabetic patients in rural tertiary centre. Int J Med Sci Public Health. 2014;3(3);405-7.

Javanbakht M, Abolhasani F, Mashayekhi A, Baradaran HR, Jahangiri Y. Health related quality of life in patients with type 2 diabetes mellitus in Iran: A national survey. PLOS ONE. 2012;7(8):44526.

Rubin RR, Peyrot M. Quality of life and diabetes. Diabetes Metab Res Rev. 1999;15:205-18.

Burroughs TE, Desikan R, Waterman BM. Development and validation of the diabetes quality of life brief clinical inventory. Diabetes Spectrum. 2004;17:41-9.

UK prospective diabetes study group. quality of life in type 2 diabetes patients is affected by complications but not by intensive policies to improve blood glucose or blood pressure control (UKPDS 37). Diabetes Care. 1999;22:1125-36.