DOI: http://dx.doi.org/10.18203/2394-6040.ijcmph20182521

Clinical profile and treatment outcome of tuberculosis patients under programmatic management in a tuberculosis unit at a tertiary care center

Avinash R. Lamb, Hrishikesh A. Khadilkar, Syed Azhar Ali Shoukat Ali

Abstract


Background: Tuberculosis (TB) is currently one of the greatest health hazards in the world, more so in India. So this study was conducted to study the clinical profile and treatment outcome of TB patients in a tuberculosis unit attached to a tertiary care centre.

Methods: A retrospective study was conducted among the tuberculosis patients attending the tuberculosis unit attached to Government Medical College, Aurangabad, Maharashtra. In which patient’s clinico-demographic profile and treatment outcome was recorded.

Results: A total of 2414 patients were included in this study of which 1377 (57.04%) were males and 1037 (42.96%) were females. The average age of patients was 33.4 years. 1811 (75.02%) patients had pulmonary, while 603 (24.98 %) patients had extra pulmonary involvement. Maximum patients were newly diagnosed type (77.51%) , while rest included defaulters, ATT (anti-tuberculous therapy) failure cases and relapse cases. 1795 patients (74.36%) belonged to category I ATT, 543 (22.49%) belonged to cat II ATT, and 76 (3.15%) belonged to category III ATT. Out of 2414 patients, 1088 (45.07%) were cured, while 834 (34.55%)successfully completed treatment. There were 232 defaulters (9.61%), 45 failures (1.86%) and 134 deaths (5.55%).

Conclusions: Though this study showed a greater predominance of pulmonary TB. It also observe high percentage extra pulmonary TB. A high positive treatment outcome noted may be attributed to the availability of specialist doctors and diagnostic facilities in the tertiary care centre.


Keywords


Tuberculosis, Clinical profile, Treatment outcome

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References


Dye C, Garnett GP, Sleeman K, Williams BG. Global burden of tuberculosis: estimated incidence, prevalence and mortality by country. J Am Med Assoc. 1999;282(7):677-86.

Ahlburg D. The economic impacts of tuberculosis. Geneva: World Health Organization; 2000.

Giri PA, Phalke DB. Impact of sensitization workshop on knowledge regarding tuberculosis among final year medical students. Int J Med Public Health. 2013;3:100-02.

Bilagi RB, Deshmukh H. Study of clinical profile of tuberculosis patients admitted in respiratory medicine ward at a tertiary care hospital in Marathwada. Int J Adv Med. 2018;5:68-72.

Ananthakrishnan R, Kumar K, Ganesh M, Kumar AMV, Krishnan N, Swaminathan S, et al. The Profile and Treatment Outcomes of the Older (Aged 60 Years and Above) Tuberculosis Patients in Tamilnadu, South India. PLoS ONE. 2013;8(7):e67288.

Lanjewar B, Bhawalkar J, Jethani S, Dhone A. Evaluation of treatment outcome of tuberculosis patients in the urban field practice area of D. Y.Patil Medical College, Pimpri, Pune. Ind J Comm Health. 2014;26(3):238-42.

Ahmed F, Shrotriya VP, Gupta SB, Kariwal P, Imtiaz D. A Study on Treatment Outcome of Tuberculosis Patients Registered at Tuberculosis Unit (TU) in Bareilly [U.P.], India. International J Curr Med Applied Sci. 2015;6(3):174-6.

Karir S, Biswas A, Mandal AK, Sagar V, Pal M. A study on clinical profile of indoor patients receiving anti-tuberculosis treatment at KPC Medical College and Hospital, Kolkata. India. Int J Community Med Public Health. 2016;3:2891-6

Giri PA, Deshpande JD, Phalke DB. Prevalence of pulmonary tuberculosis among HIV positive patients attending antiretroviral therapy clinic. North Am J Med Sci. 2013;5:367-70

Brahmapurkar KP, Brahmapurkar VK, Khan QH. Treatment Outcome of Registered Tuberculosis Cases for Year 2013 in Tuberculosis Unit in Tribal District Bastar of Chhattisgarh, India. Natl J Community Med. 2016;7(5):377-81.

Motghare DD, Sardessai GM, Vaz FS, Kulkarni MS. Study of treatment outcomes in tuberculosis patients on DOTS therapy at five centres in Goa. Int J Community Med Public Health. 2014;1(1):48-51.