DOI: http://dx.doi.org/10.18203/2394-6040.ijcmph20182038

A community based screening of gestational diabetes mellitus within 16 weeks of pregnancy: a study from Mysuru district, Karnataka

Abhishek Kumar Sinha, Madhu B., Narayana Murthy M. R.

Abstract


Background: Gestational diabetes mellitus is defined as carbohydrate intolerance with onset/recognition during pregnancy where maternal and perinatal complications are increased. Aged care facilities in rural areas reports disparity in the management of gestational diabetes as compared with urban counter parts. As a need to address this, study conducted with objective to estimate prevalence of gestational diabetes mellitus within 16 weeks of gestation for GDM by oral glucose challenges test.

Methods: Antenatal mothers attending primary health centers within 16 weeks of gestation were screened for GDM. Two hours, venous samples were calculated for estimation of blood glucose level. Plasma glucose level of >140mg/dl was considered as OGTT positive.

Results: Among 301 patients examined 11 mothers had OGTT positive results. GDM was seen in 3.7% of Mothers. GDM is found significantly associated with increasing age (p=0.01, t=2.52, mean difference 2.54 CI 0.5-4.5), weight (p=0.04, t=2.24, mean difference 10.8 CI 0.11-21.5), and BMI (p<0.01, t=2.97, mean difference 3.6 CI 1.2-6). GDM was seen more in multigravida (P=0.01). Statistically significant association of GDM was found with mean systolic (p<0.01, t=2.62, mean difference 8.08 CI 2.01-14.14) and diastolic blood pressure (P<0.01, t=3.44, mean difference 7.87 CI 3.38-12.36). A multiple regression shows these variables statistically significantly predicted GDM, F (5, 295)= 7, p<0.001, R2=0.106.

Conclusions: GDM is statistically associated with increasing age, increasing weight, BMI and multiple gravida in pregnancy. It is recommended to screen for GDM within the 1st trimester & follow up needed to prevent further complications.


Keywords


Gestational diabetes mellitus, Antenatal mothers, Rural

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References


Lepercq J. Fetal complications of GDM. In: Diapedia. Diapedia.org; 2013. Available at: http://www.diapedia.org/41040851409/rev/13. Accessed on 4 April 2018.

Aune D, Sen A, Henriksen T, Saugstad OD, Tonstad S. Physical activity and the risk of gestational diabetes mellitus: a systematic review and dose–response meta-analysis of epidemiological studies. Eur J Epidemiol. 2016;31(10):967–97.

Pons RS, Rockett FC, de Almeida Rubin B, Oppermann MLR, Bosa VL. Risk factors for gestational diabetes mellitus in a sample of pregnant women diagnosed with the disease. Diabetol Metab Syndr. 2015;7(1):80.

Rajput M, Bairwa M, Rajput R. Prevalence of gestational diabetes mellitus in rural Haryana: A community-based study. Indian J Endocrinol Metab. 2014;18(3):350–4.

Bhatt AA, Dhore PB, Purandare VB, Sayyad MG, Mandal MK, Unnikrishnan AG. Gestational diabetes mellitus in rural population of Western India – Results of a community survey. Indian J Endocrinol Metab. 2015;19(4):507–10.

Gupta K, Parmar M, Dubey S. Incidence of Gestational Diabetes Mellitus in Pregnant women from Rural Background Attending Antenatal Care Clinic. Int J Med Res Rev. 2015;3(02).

Varghese R, Thomas B, Hail DMA, Rauf DA, Sadi DMA, Sualiti DAA, et al. The Prevalence, Risk Factors, Maternal and Fetal outcomes in Gestational Diabetes Mellitus. Int J Drug Development Res. 2012;4(3).

Nahum GG, Wilson SB, Stanislaw H. Early-pregnancy glucose screening for gestational diabetes mellitus. J Reprod Med. 2002;47(8):656–62.

Bhavadharini B, Mahalakshmi MM, Anjana RM, Maheswari K, Uma R, Deepa M, et al. Prevalence of Gestational Diabetes Mellitus in urban and rural Tamil Nadu using IADPSG and WHO 1999 criteria (WINGS 6). Clin Diabetes Endocrinol. 2016:2.

Carolan M, Davey M-A, Biro MA, Kealy M. Maternal age, ethnicity and gestational diabetes mellitus. Midwifery. 2012;28(6):778–83.

Bryson CL, Ioannou GN, Rulyak SJ, Critchlow C. Association between Gestational Diabetes and Pregnancy-induced Hypertension. Am J Epidemiol. 2003;158(12):1148–53.

Yuan X, Liu H, Wang L, Zhang S, Zhang C, Leng J, et al. Gestational hypertension and chronic hypertension on the risk of diabetes among gestational diabetes women. J Diabetes Complications. 2016;30(7):1269–74.

Perveen S, Jabeen Q, Iqbal MZ. Relationship between gestational diabetes and pregnancy induced hypertension (PIH), Int Current Pharma J. 2015;4(11):453-6.